LH supplementation of ovarian stimulation protocols influences follicular fluid steroid composition contributing to the improvement of ovarian response in poor responder women.
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ABSTRACT:
SUBMITTER: Marchiani S
PROVIDER: S-EPMC7395161 | biostudies-literature | 2020 Jul
REPOSITORIES: biostudies-literature
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LH supplementation of ovarian stimulation protocols influences follicular fluid steroid composition contributing to the improvement of ovarian response in poor responder women.
Marchiani S S Tamburrino L L Benini F F Pallecchi M M Bignozzi C C Conforti A A Alviggi C C Vignozzi L L Danza G G Pellegrini S S Baldi E E
Scientific reports 20200731 1
In this prospective study, we evaluated the steroid levels in 111 follicular fluids (FF) collected from 13 women stimulated with FSH monotherapy and 205 FF collected from 28 women stimulated with FSH + LH because of a previous history of hypo-responsiveness to FSH. Steroid levels were measured by HPLC/MS-MS and related to ovarian stimulation protocol, oocyte maturity, fertilization and quality of blastocysts, after individually tracking the fate of all retrieved oocytes. 17-Hydroxy-Progesterone, ...[more]
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