Ontology highlight
ABSTRACT:
SUBMITTER: Fogagnolo P
PROVIDER: S-EPMC7395393 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
BMC ophthalmology 20200801 1
<h4>Background</h4>To evaluate the effects of topical citicoline and vitamin B12 (Cit-B12: OMK2, Omikron Italia srl, Italy) on corneal innervation of patients with diabetic neuropathy.<h4>Methods</h4>This prospective, randomized, double blind, placebo-controlled study included 30 patients randomised with a 2:1 ratio to Cit-B12 or placebo 3 times daily for 18 months. At baseline and at months 4, 8, 12, 18 patients underwent the Ocular Surface Disease Index questionnaire (OSDI), tear break-up time ...[more]