Ontology highlight
ABSTRACT:
SUBMITTER: Xie Q
PROVIDER: S-EPMC7399223 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Xie Qiubo Q Tang Tang T Pang Jian J Xu Jing J Yang Xingxia X Wang Linang L Huang Yiqiang Y Huang Zhuowei Z Liu Gaolei G Tong Dali D Zhang Yao Y Wang Luofu L Zhang Dianzheng D Lan Weihua W Liu Qiuli Q Jiang Jun J
Frontiers in oncology 20200728
Epithelial-to-mesenchymal transition (EMT) is one of the important underlying molecular mechanisms for most types of cancers including bladder cancer. The precise underlying molecular mechanism in EMT-mediated bladder cancer progression is far from completed. LSD1, a histone lysine-specific demethylase, is known to promote cancer cell proliferation, metastasis, and chemoresistance. We found in this study that LSD1 is highly upregulated in bladder cancer specimens, especially those underwent chem ...[more]