Unknown

Dataset Information

0

Molecular epidemiology of Aleutian mink disease virus causing outbreaks in mink farms from Southwestern Europe: a retrospective study from 2012 to 2019.


ABSTRACT: BACKGROUND:Aleutian mink disease virus (AMDV) causes major economic losses in fur-bearing animal production. The control of most AMDV outbreaks is complex due to the difficulties of establishing the source of infection based only on the available on-farm epidemiological data. In this sense, phylogenetic analysis of the strains present in a farm may help elucidate the origin of the infection and improve the control and biosecurity measures. OBJECTIVES:This study had the following aims: characterize the AMDV strains from most outbreaks produced at Spanish farms between 2012-2019 at the molecular level, and assess the utility of the combined use of molecular and epidemiological data to track the possible routes of infection. METHODS:Thirty-seven strains from 17 farms were partially sequenced for the NS1 and VP2 genes and analyzed phylogenetically with other strains described worldwide. RESULTS:Spanish AMDV strains are clustered in four major clades that generally show a good geographical correlation, confirming that most had been established in Spain a long time ago. The combined study of phylogenetic results and epidemiological information of each farm suggests that most of the AMDV outbreaks since 2012 had been produced by within-farm reservoirs, while a few of them may have been due to the introduction of the virus through international trade. CONCLUSIONS:The combination of phylogenetic inference, together with epidemiological data, helps assess the possible origin of AMDV infections in mink farms and improving the control and prevention of this disease.

SUBMITTER: Prieto A 

PROVIDER: S-EPMC7402935 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature

altmetric image

Publications

Molecular epidemiology of Aleutian mink disease virus causing outbreaks in mink farms from Southwestern Europe: a retrospective study from 2012 to 2019.

Prieto Alberto A   Fernández-Antonio Ricardo R   López-Lorenzo Gonzalo G   Díaz-Cao José Manuel JM   López-Novo Cynthia C   Remesar Susana S   Panadero Rosario R   Díaz Pablo P   Morrondo Patrocinio P   Díez-Baños Pablo P   Fernández Gonzalo G  

Journal of veterinary science 20200701 4


<h4>Background</h4>Aleutian mink disease virus (AMDV) causes major economic losses in fur-bearing animal production. The control of most AMDV outbreaks is complex due to the difficulties of establishing the source of infection based only on the available on-farm epidemiological data. In this sense, phylogenetic analysis of the strains present in a farm may help elucidate the origin of the infection and improve the control and biosecurity measures.<h4>Objectives</h4>This study had the following a  ...[more]

Similar Datasets

| S-EPMC7395569 | biostudies-literature
| S-EPMC8153481 | biostudies-literature
| S-EPMC3353359 | biostudies-literature
| S-EPMC4379071 | biostudies-literature
| S-EPMC6110490 | biostudies-literature
| S-EPMC8549281 | biostudies-literature
| S-EPMC8451439 | biostudies-literature
| S-EPMC85904 | biostudies-literature
| S-EPMC7859209 | biostudies-literature
| S-EPMC5700682 | biostudies-literature