Ontology highlight
ABSTRACT:
SUBMITTER: Vo AQ
PROVIDER: S-EPMC7403534 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Vo Anh Q AQ Zhang Jiaxiang J Nyavanandi Dinesh D Bandari Suresh S Repka Michael A MA
Carbohydrate polymers 20200604
Three-dimensional printing could serve as a platform to fabricate individualized medicines and complex-structured solid dosage forms. Herein, hot melt extrusion was coupled with 3D printing to develop a unique gastro retentive dosage form to personalize treatment of cinnarizine or other narrow absorption window drugs. The mechanical strength of the extruded strands was optimized for printing by combining two polymers, hydroxypropyl cellulose and vinylpyrrolidone vinyl acetate copolymer. The unit ...[more]