Ontology highlight
ABSTRACT:
SUBMITTER: Lu G
PROVIDER: S-EPMC7409388 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Frontiers in medicine 20200730
The 78-kDa glucose-regulated protein (GRP78) plays an important part in maintaining protein stability, regulating protein folding, and inducing apoptosis autophagy, which is considered as a powerful protein. Meanwhile, it also plays a role in ensuring the normal function of organs. In recent years, more and more researches have been carried out on the targeted therapy of GRP78, mainly focusing on its relevant role in tumor and its role as a major modulator and modulator of subordinate pathways. ...[more]