Ontology highlight
ABSTRACT:
SUBMITTER: Gratz L
PROVIDER: S-EPMC7414126 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Grätz Lukas L Tropmann Katharina K Bresinsky Merlin M Müller Christoph C Bernhardt Günther G Pockes Steffen S
Scientific reports 20200806 1
Fluorescence/luminescence-based techniques play an increasingly important role in the development of test systems for the characterization of future drug candidates, especially in terms of receptor binding in the field of G protein-coupled receptors (GPCRs). In this article, we present the establishment of a homogeneous live cell-based BRET binding assay for the histamine H<sub>2</sub> receptor with different fluorescently labeled squaramide-type compounds synthesized in the course of this study ...[more]