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The association between cardiac injury and outcomes in hospitalized patients with COVID-19.


ABSTRACT: In this study, we aimed to assess the association between development of cardiac injury and short-term mortality as well as poor in-hospital outcomes in hospitalized patients with COVID-19. In this prospective, single-center study, we enrolled hospitalized patients with laboratory-confirmed COVID-19 and highly suspicious patients with compatible chest computed tomography features. Cardiac injury was defined as a rise of serum high sensitivity cardiac Troponin-I level above 99th percentile (men:?>?26 ng/mL, women:?>?11 ng/mL). A total of 386 hospitalized patients with COVID-19 were included. Cardiac injury was present among 115 (29.8%) of the study population. The development of cardiac injury was significantly associated with a higher in-hospital mortality rate compared to those with normal troponin levels (40.9% vs 11.1%, p value?

SUBMITTER: Karbalai Saleh S 

PROVIDER: S-EPMC7415198 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature

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The association between cardiac injury and outcomes in hospitalized patients with COVID-19.

Karbalai Saleh Shahrokh S   Oraii Alireza A   Soleimani Abbas A   Hadadi Azar A   Shajari Zahra Z   Montazeri Mahnaz M   Moradi Hedieh H   Talebpour Mohammad M   Sadat Naseri Azadeh A   Balali Pargol P   Akhbari Mahsa M   Ashraf Haleh H  

Internal and emergency medicine 20200809 8


In this study, we aimed to assess the association between development of cardiac injury and short-term mortality as well as poor in-hospital outcomes in hospitalized patients with COVID-19. In this prospective, single-center study, we enrolled hospitalized patients with laboratory-confirmed COVID-19 and highly suspicious patients with compatible chest computed tomography features. Cardiac injury was defined as a rise of serum high sensitivity cardiac Troponin-I level above 99th percentile (men:   ...[more]

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