Ontology highlight
ABSTRACT:
SUBMITTER: Guo L
PROVIDER: S-EPMC7417440 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Frontiers in chemistry 20200804
Chemical investigation of a marine-derived <i>Streptomyces</i> sp. KCB-132, cultivated in liquid ISP2 medium, had led to the discovery of three C-ring cleavage angucyclinone <i>N</i>-heterocycles, pratensilins A-C, with a novel spiro indolinone-naphthofuran skeleton. Addition of 50 μM LaCl<sub>3</sub> to the same medium and subsequent chemical analysis of this strain returned a new member of this rare class, pratensilin D (<b>1</b>), along with two new angucyclinone derivatives, featuring ether- ...[more]