Ontology highlight
ABSTRACT:
SUBMITTER: Taubenberger AV
PROVIDER: S-EPMC7423972 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Taubenberger Anna V AV Baum Buzz B Matthews Helen K HK
Frontiers in cell and developmental biology 20200806
When animal cells enter mitosis, they round up to become spherical. This shape change is accompanied by changes in mechanical properties. Multiple studies using different measurement methods have revealed that cell surface tension, intracellular pressure and cortical stiffness increase upon entry into mitosis. These cell-scale, biophysical changes are driven by alterations in the composition and architecture of the contractile acto-myosin cortex together with osmotic swelling and enable a mitoti ...[more]