Ontology highlight
ABSTRACT:
SUBMITTER: Akanuma T
PROVIDER: S-EPMC4931277 | biostudies-literature | 2016 Jun
REPOSITORIES: biostudies-literature
Akanuma Takashi T Chen Cong C Sato Tetsuo T Merks Roeland M H RM Sato Thomas N TN
Nature communications 20160628
Cell shape influences function, and the current model suggests that such shape effect is transient. However, cells dynamically change their shapes, thus, the critical question is whether shape information remains influential on future cell function even after the original shape is lost. We address this question by integrating experimental and computational approaches. Quantitative live imaging of asymmetric cell-fate decision-making and their live shape manipulation demonstrates that cellular ec ...[more]