Obesity-induced inflammation and insulin resistance: A mini-review on T-cells.
Ontology highlight
ABSTRACT:
SUBMITTER: Nyambuya TM
PROVIDER: S-EPMC7424835 | biostudies-literature | 2019 Sep
REPOSITORIES: biostudies-literature
Publications
Obesity-induced inflammation and insulin resistance: A mini-review on T-cells.
Nyambuya Tawanda Maurice TM Dludla Phiwayinkosi Vusi PV Mxinwa Vuyolwethu V Nkambule Bongani Brian BB
Metabolism open 20190810
Excessive lipid accumulation in an obese state is linked with activation and release of detrimental cytokines and chemokines that promote metabolic dysregulation. In fact, emerging experimental evidence shows that abnormal modulation of T-cells in an obese state correlates with the development and progression of insulin resistance. Importantly, the evolving concept linking insulin resistance with impaired immunological mechanisms such as T-cell responses provides new prospects for understanding ...[more]
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