Ontology highlight
ABSTRACT:
SUBMITTER: Yu S
PROVIDER: S-EPMC7428627 | biostudies-literature | 2020 Apr
REPOSITORIES: biostudies-literature
Yu Shikai S Middlemiss Jessica E JE Nardin Chiara C Hickson Stacey S SS Miles Karen L KL Yasmin Maki-Petaja Kaisa M KM McDonnell Barry J BJ Cockcroft John R JR Wilkinson Ian B IB McEniery Carmel M CM
Journal of the American Heart Association 20200330 7
Background Two individuals can have a similar pulse pressure (PP) but different levels of systolic blood pressure (SBP), although the underlying mechanisms have not been described. We hypothesized that, for a given level of PP, differences in SBP relate to peripheral vascular resistance (PVR); and we tested this hypothesis in a large cohort of healthy young adults. Methods and Results Demographic, biochemical, and hemodynamic data from 3103 subjects were available for the current analyses. In bo ...[more]