Ontology highlight
ABSTRACT:
SUBMITTER: Torroglosa A
PROVIDER: S-EPMC7432910 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Torroglosa Ana A Villalba-Benito Leticia L Fernández Raquel María RM Luzón-Toro Berta B Moya-Jiménez María José MJ Antiñolo Guillermo G Borrego Salud S
International journal of molecular sciences 20200802 15
Hirschsprung disease (HSCR) is a neurocristopathy defined by intestinal aganglionosis due to alterations during the development of the Enteric Nervous System (ENS). A wide spectrum of molecules involved in different signaling pathways and mechanisms have been described in HSCR onset. Among them, epigenetic mechanisms are gaining increasing relevance. In an effort to better understand the epigenetic basis of HSCR, we have performed an analysis for the identification of long non-coding RNAs (lncRN ...[more]