Ontology highlight
ABSTRACT:
SUBMITTER: Rekha UV
PROVIDER: S-EPMC7434954 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Bioinformation 20200531 5
Piperine is a component of Piper nigrum (Black pepper). It is well known in ayurvedic formulations. Piperine is a bioenhancer as it reduces the activity of drug-metabolizing enzymes in rodents and thereby enhancing the plasma concentrations of several drugs, including the Pglycoprotein substrates. Therefore, it is of interest to understand the molecular docking interactions of piperine with several cell cycle proteins such as Cyclin dependent kinase 2 (CDK2), Cyclin-dependent kinase 4 (CDK4), Cy ...[more]