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Accounting for indirect protection in the benefit-risk ratio estimation of rotavirus vaccination in children under the age of 5 years, France, 2018.


ABSTRACT: Background

SUBMITTER: Escolano S 

PROVIDER: S-EPMC7441603 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature

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Accounting for indirect protection in the benefit-risk ratio estimation of rotavirus vaccination in children under the age of 5 years, France, 2018.

Escolano Sylvie S   Mueller Judith E JE   Tubert-Bitter Pascale P  

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20200801 33


Background Rotavirus is a major cause of severe gastroenteritis in children worldwide. The disease burden has been substantially reduced in countries where rotavirus vaccines are used. Given the risk of vaccine-induced intussusception, the benefit–risk balance of rotavirus vaccination has been assessed in several countries, however mostly without considering indirect protection effects. Aim We performed a benefit–risk analysis of rotavirus vaccination accounting for indirect protection in Franc  ...[more]

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