Dataset Information

Laryngopharyngeal reflux in chronic obstructive pulmonary disease - a multi-centre study.

ABSTRACT: Reflux of gastric content has been associated with recurrent exacerbations of chronic obstructive pulmonary disease (COPD). We aimed to assess the prevalence of laryngopharyngeal reflux (LPR) in COPD and if LPR is a contributing factor to clinically relevant outcomes in COPD. We evaluated a total of 193 COPD patients (GOLD I-IV) with a 24-h laryngo-pharyngeal p?-monitor. LPR was observed in 65.8% of COPD patients and it was not significantly associated with clinically relevant outcomes of COPD. Treatment with PPI significantly decreased the upright RYAN score (p?=?0.047) without improving lung function. Furthermore, the presence or severity of LPR cannot be diagnosed based solely on symptoms and questionnaires.

SUBMITTER: Sanchez J

PROVIDER: S-EPMC7441701 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature

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Laryngopharyngeal reflux in chronic obstructive pulmonary disease - a multi-centre study.

Sanchez Julia J Schumann Desiree M DM Karakioulaki Meropi M Papakonstantinou Eleni E Rassouli Frank F Frasnelli Matthias M Brutsche Martin M Tamm Michael M Stolz Daiana D

Respiratory research 20200821 1

Reflux of gastric content has been associated with recurrent exacerbations of chronic obstructive pulmonary disease (COPD). We aimed to assess the prevalence of laryngopharyngeal reflux (LPR) in COPD and if LPR is a contributing factor to clinically relevant outcomes in COPD. We evaluated a total of 193 COPD patients (GOLD I-IV) with a 24-h laryngo-pharyngeal pΗ-monitor. LPR was observed in 65.8% of COPD patients and it was not significantly associated with clinically relevant outcomes of COPD. ...[more]

PMID: 32825819

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Dataset Information

Laryngopharyngeal reflux in chronic obstructive pulmonary disease - a multi-centre study.

Publications

Laryngopharyngeal reflux in chronic obstructive pulmonary disease - a multi-centre study.

Similar Datasets

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