Ontology highlight
ABSTRACT:
SUBMITTER: Eng VV
PROVIDER: S-EPMC7448748 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Eng Vik Ven VV Wemyss Madeleine A MA Pearson Jaclyn S JS
Seminars in cell & developmental biology 20200826
Receptor Interacting Protein Kinases (RIPKs) are cellular signaling molecules that are critical for homeostatic signaling in both communicable and non-communicable disease processes. In particular, RIPK1, RIPK2, RIPK3 and RIPK7 have emerged as key mediators of intracellular signal transduction including inflammation, autophagy and programmed cell death, and are thus essential for the early control of many diverse pathogenic organisms. In this review, we discuss the role of each RIPK in host resp ...[more]