Ontology highlight
ABSTRACT:
SUBMITTER: Mariscal J
PROVIDER: S-EPMC7448892 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Mariscal Javier J Vagner Tatyana T Kim Minhyung M Zhou Bo B Chin Andrew A Zandian Mandana M Freeman Michael R MR You Sungyong S Zijlstra Andries A Yang Wei W Di Vizio Dolores D
Journal of extracellular vesicles 20200610 1
Extracellular vesicles (EVs) are membrane-enclosed particles that play an important role in cancer progression and have emerged as a promising source of circulating biomarkers. Protein <i>S</i>-acylation, frequently called palmitoylation, has been proposed as a post-translational mechanism that modulates the dynamics of EV biogenesis and protein cargo sorting. However, technical challenges have limited large-scale profiling of the whole palmitoyl-proteins of EVs. We successfully employed a novel ...[more]