Ontology highlight
ABSTRACT:
SUBMITTER: Zocher S
PROVIDER: S-EPMC7449688 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Zocher Sara S Schilling Susan S Grzyb Anna N AN Adusumilli Vijay S VS Bogado Lopes Jadna J Günther Sandra S Overall Rupert W RW Winter York Y Kempermann Gerd G
Science advances 20200826 35
Individuals differ in their response to environmental stimuli, but the stability of individualized behaviors and their associated changes in brain plasticity are poorly understood. We developed a novel model of enriched environment to longitudinally monitor 40 inbred mice exploring 35 connected cages over periods of 3 to 6 months. We show that behavioral individuality that emerged during the first 3 months of environmental enrichment persisted when mice were withdrawn from the enriched environme ...[more]