Microphysiological sensing platform for an in-situ detection of tissue-secreted cytokines.
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ABSTRACT:
SUBMITTER: Hernandez-Albors A
PROVIDER: S-EPMC7453918 | biostudies-literature | 2019 Oct
REPOSITORIES: biostudies-literature
Publications
Microphysiological sensing platform for an in-situ detection of tissue-secreted cytokines.
Hernández-Albors Alejandro A Castaño Albert G AG Fernández-Garibay Xiomara X Ortega María Alejandra MA Balaguer Jordina J Ramón-Azcón Javier J
Biosensors & bioelectronics: X 20191001
Understanding the protein-secretion dynamics from single, specific tissues is critical toward the advancement of disease detection and treatments. However, such secretion dynamics remain difficult to measure in vivo due to the uncontrolled contributions from other tissue populations. Here, we describe an integrated platform designed for the reliable, near real-time measurements of cytokines secreted from an in vitro single-tissue model. In our setup, we grow 3D biomimetic tissues to discretize c ...[more]
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