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Severe Acute Respiratory Syndrome Coronavirus 2 Prevalence, Seroprevalence, and Exposure among Evacuees from Wuhan, China, 2020.


ABSTRACT: To determine prevalence of, seroprevalence of, and potential exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among a cohort of evacuees returning to the United States from Wuhan, China, in January 2020, we conducted a cross-sectional study of quarantined evacuees from 1 repatriation flight. Overall, 193 of 195 evacuees completed exposure surveys and submitted upper respiratory or serum specimens or both at arrival in the United States. Nearly all evacuees had taken preventive measures to limit potential exposure while in Wuhan, and none had detectable SARS-CoV-2 in upper respiratory tract specimens, suggesting the absence of asymptomatic respiratory shedding among this group at the time of testing. Evidence of antibodies to SARS-CoV-2 was detected in 1 evacuee, who reported experiencing no symptoms or high-risk exposures in the previous 2 months. These findings demonstrated that this group of evacuees posed a low risk of introducing SARS-CoV-2 to the United States.

SUBMITTER: Hallowell BD 

PROVIDER: S-EPMC7454104 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature

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Severe Acute Respiratory Syndrome Coronavirus 2 Prevalence, Seroprevalence, and Exposure among Evacuees from Wuhan, China, 2020.

Hallowell Benjamin D BD   Carlson Christina M CM   Jacobs Jesica R JR   Pomeroy Mary M   Steinberg Jonathan J   Tenforde Mark W MW   McDonald Emily E   Foster Loretta L   Feldstein Leora R LR   Rolfes Melissa A MA   Haynes Amber A   Abedi Glen R GR   Odongo George S GS   Saruwatari Kim K   Rider Errin C EC   Douville Gina G   Bhakta Neenaben N   Maniatis Panagiotis P   Lindstrom Stephen S   Thornburg Natalie J NJ   Lu Xiaoyan X   Whitaker Brett L BL   Kamili Shifaq S   Sakthivel Senthilkumar K SK   Wang Lijuan L   Malapati Lakshmi L   Murray Janna R JR   Lynch Brian B   Cetron Martin M   Brown Clive C   Roohi Shahrokh S   Rotz Lisa L   Borntrager Denise D   Ishii Kenta K   Moser Kathleen K   Rasheed Mohammad M   Freeman Brandi B   Lester Sandra S   Corbett Kizzmekia S KS   Abiona Olubukola M OM   Hutchinson Geoffrey B GB   Graham Barney S BS   Pesik Nicki N   Mahon Barbara B   Braden Christopher C   Behravesh Casey Barton CB   Stewart Rebekah R   Knight Nancy N   Hall Aron J AJ   Killerby Marie E ME  

Emerging infectious diseases 20200703 9


To determine prevalence of, seroprevalence of, and potential exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among a cohort of evacuees returning to the United States from Wuhan, China, in January 2020, we conducted a cross-sectional study of quarantined evacuees from 1 repatriation flight. Overall, 193 of 195 evacuees completed exposure surveys and submitted upper respiratory or serum specimens or both at arrival in the United States. Nearly all evacuees had taken preve  ...[more]

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