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First European report of Francisella tularensis subsp. holarctica isolation from a domestic cat.

ABSTRACT: Francisella tularensis subsp. holarctica is a select agent causing life-threatening tularemia. It has been isolated from humans and animals, mainly lagomorphs and rodents, rarely other wild carnivore species. Increasing numbers of human tularemia cases have been reported during the last 5 years in Switzerland. Here we report the first isolation of Francisella tularensis subsp. holarctica from a domestic cat in Europe and compare its genome sequence with other Swiss isolates. The cat isolate shows a close phylogenetic relationship with a contemporary hare isolate from close geographic proximity, indicating a possible epidemiological link.

SUBMITTER: Kittl S

PROVIDER: S-EPMC7457513 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature

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First European report of Francisella tularensis subsp. holarctica isolation from a domestic cat.

Kittl Sonja S Francey Thierry T Brodard Isabelle I Origgi Francesco C FC Borel Stéphanie S Ryser-Degiorgis Marie-Pierre MP Schweighauser Ariane A Jores Joerg J

Veterinary research 20200831 1

Francisella tularensis subsp. holarctica is a select agent causing life-threatening tularemia. It has been isolated from humans and animals, mainly lagomorphs and rodents, rarely other wild carnivore species. Increasing numbers of human tularemia cases have been reported during the last 5 years in Switzerland. Here we report the first isolation of Francisella tularensis subsp. holarctica from a domestic cat in Europe and compare its genome sequence with other Swiss isolates. The cat isolate show ...[more]

PMID: 32867856

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