Ontology highlight
ABSTRACT:
SUBMITTER: Xie H
PROVIDER: S-EPMC7461581 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
International journal of molecular sciences 20200813 16
Gastric cancer is the most common malignant tumor of the digestive tract and is great challenge in clinical treatment. N6-(2-Hydroxyethyl)-adenosine (HEA), widely present in various fungi, is a natural adenosine derivative with many biological and pharmacological activities. Here, we assessed the antineoplastic effect of HEA on gastric carcinoma. HEA exerted cytotoxic effects against gastric carcinoma cells (SGC-7901 and AGS) in a dose and time-dependent manner. Additionally, we found that HEA i ...[more]