Ontology highlight
ABSTRACT:
SUBMITTER: Yue GG
PROVIDER: S-EPMC7463810 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Yue Grace Gar-Lee GG Gao Si S Lee Julia Kin-Ming JK Chan Yuk-Yu YY Wong Eric Chun-Wai EC Zheng Tao T Li Xiao-Xiao XX Shaw Pang-Chui PC Simmonds Monique S J MSJ Lau Clara Bik-San CB
Molecules (Basel, Switzerland) 20200815 16
Tricin, a flavone isolated from rice bran, has been shown to be chemopreventive in a colorectal cancer (CRC) mouse model. This study aimed to illustrate the inhibitory activities of tricin in colon cancer cells and in a metastatic CRC mouse model. BALB/c mice injected with mouse Colon26-Luc cells into the rectum wall were treated with tricin (37.5 mg/kg) daily for 18 days. Orthotopic colon tumor growth and metastasis to lungs were assessed by in vivo bioluminescence imaging. Results showed that ...[more]