Ontology highlight
ABSTRACT:
SUBMITTER: Picos A
PROVIDER: S-EPMC7465525 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Picos Andrei A Vulturar Romana R Picos Alina A Chis Adina A Chiorean Ioana I Piciu Andra A Petrachescu Narcisa N Dumitrascu Dan L DL
Experimental and therapeutic medicine 20200723 4
Inflammation may play contradictory roles in the pathogenesis of gastroesophageal reflux disease (GERD): gastritis decreases gastric output and reduces the risk of esophagitis, while interleukins may favor mucosal inflammation. The inflammation may cause esogastric motility changes and thus increase the risk of esophagitis. Considering the genetic influence of inflammatory response, we looked for the genetic polymorphisms of IL-1 in GERD manifested as reflux esophagitis. This is a prospective st ...[more]