Genome-Wide Association Analysis Identified ANXA1 Associated with Shoulder Impingement Syndrome in UK Biobank Samples.
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ABSTRACT:
SUBMITTER: Cheng B
PROVIDER: S-EPMC7466970 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
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Genome-Wide Association Analysis Identified ANXA1 Associated with Shoulder Impingement Syndrome in UK Biobank Samples.
Cheng Bolun B Ning Yujie Y Liang Chujun C Li Ping P Liu Li L Cheng Shiqiang S Ma Mei M Zhang Lu L Qi Xin X Wen Yan Y Zhang Feng F
G3 (Bethesda, Md.) 20200902 9
Shoulder impingement syndrome (SIS) is a common shoulder disorder with unclear genetic mechanism. In this study, Genome-wide Association Study (GWAS) was conducted to identify the candidate loci associated with SIS by using the UK Biobank samples (including 3,626 SIS patients and 3,626 control subjects). Based on the GWAS results, gene set enrichment analysis was further performed to detect the candidate gene ontology and pathways associated with SIS. We identified multiple risk loci associated ...[more]
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