[Pharmacology and Clinical Evaluation of Ensartinib Hydrochloride Capsule].
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ABSTRACT:
SUBMITTER: Wang Y
PROVIDER: S-EPMC7467989 | biostudies-literature | 2020 Aug
REPOSITORIES: biostudies-literature
Publications
[Pharmacology and Clinical Evaluation of Ensartinib Hydrochloride Capsule].
Wang Yang Y Yuan Xiaobin X Xiong Jiayan J Hao Zhidong Z Peng Xingzhe X Chen Wanlin W Cui Lingling L Li Hua H Wang Xiulan X He Xiangbo X Yang Min M Liang Congxin C Ma Yongbin Y Ding Lieming L Mao Li L
Zhongguo fei ai za zhi = Chinese journal of lung cancer 20200801 8
Lung cancer is one of the most common malignancies with the highest incidence rate and mortality rate worldwide, and non-small cell lung cancer (NSCLC) accounts for about 85%. Only 5% NSCLC patients are anaplastic lymphoma kinase (ALK) rearrangement positive NSCLC, but the prognosis of these patients is poor, and treatment is urgent. Ensartinib (X-396), a next-generation ALK tyrosine kinase inhibitor (ALK-TKI), has shown greater potency on inhibiting ALK activity and controlling brain metastases ...[more]
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