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Phosphoranyl Radical Fragmentation Reactions Driven by Photoredox Catalysis.

ABSTRACT: Photocatalytic generation of phosphoranyl radicals is fast emerging as an essential method for the generation of diverse and valuable radicals, typically via deoxygenation or desulfurization processes. This Perspective is a comprehensive evaluation of all studies using phosphoranyl radicals as tunable mediators in photoredox catalysis, highlighting how two distinct methods for phosphoranyl radical formation (radical addition and nucleophilic addition) can be used to generate versatile radical intermediates with diverse reactivity profiles.

SUBMITTER: Rossi-Ashton JA

PROVIDER: S-EPMC7469205 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature

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Phosphoranyl Radical Fragmentation Reactions Driven by Photoredox Catalysis.

Rossi-Ashton James A JA Clarke Aimee K AK Unsworth William P WP Taylor Richard J K RJK

ACS catalysis 20200605 13

Photocatalytic generation of phosphoranyl radicals is fast emerging as an essential method for the generation of diverse and valuable radicals, typically via deoxygenation or desulfurization processes. This Perspective is a comprehensive evaluation of all studies using phosphoranyl radicals as tunable mediators in photoredox catalysis, highlighting how two distinct methods for phosphoranyl radical formation (radical addition and nucleophilic addition) can be used to generate versatile radical in ...[more]

PMID: 32905246

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