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Surgical site infection after hip fracture surgery: a systematic review and meta-analysis of studies published in the UK.


ABSTRACT: Aims:This study explores the reported rate of surgical site infection (SSI) after hip fracture surgery in published studies concerning patients treated in the UK. Methods:Studies were included if they reported on SSI after any type of surgical treatment for hip fracture. Each study required a minimum of 30 days follow-up and 100 patients. Meta-analysis was undertaken using a random effects model. Heterogeneity was expressed using the I2 statistic. Risk of bias was assessed using a modified Newcastle-Ottawa Scale (NOS) system. Results:There were 20 studies reporting data from 88,615 patients. Most were retrospective cohort studies from single centres. The pooled incidence was 2.1% (95% confidence interval (CI) 1.54% to 2.62%) across 'all types' of hip fracture surgery. When analyzed by operation type, the SSI incidences were: hemiarthroplasty 2.87% (95% CI 1.99% to 3.75%) and sliding hip screw 1.35% (95% CI 0.78% to 1.93%). There was considerable variation in definition of infection used, as well as considerable risk of bias, particularly as few studies actively screened participants for SSI. Conclusion:Synthesis of published estimates of infection yield a rate higher than that seen in national surveillance procedures. Biases noted in all studies would trend towards an underestimate, largely due to inadequate follow-up.

SUBMITTER: Masters J 

PROVIDER: S-EPMC7469514 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature

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Surgical site infection after hip fracture surgery: a systematic review and meta-analysis of studies published in the UK.

Masters James J   Metcalfe David D   Ha Joon Soo JS   Judge Andrew A   Costa Matthew L ML  

Bone & joint research 20200903 9


<h4>Aims</h4>This study explores the reported rate of surgical site infection (SSI) after hip fracture surgery in published studies concerning patients treated in the UK.<h4>Methods</h4>Studies were included if they reported on SSI after any type of surgical treatment for hip fracture. Each study required a minimum of 30 days follow-up and 100 patients. Meta-analysis was undertaken using a random effects model. Heterogeneity was expressed using the I<sup>2</sup> statistic. Risk of bias was asses  ...[more]

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