Genetic Engineering to Induce Fetal-Like Hematopoietic Stem Cells.
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ABSTRACT:
SUBMITTER: Ulum B
PROVIDER: S-EPMC7470128 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Publications
Genetic Engineering to Induce Fetal-Like Hematopoietic Stem Cells.
Ulum Bariş B Muljo Stefan A SA
Gene technology 20200101 3
Bone marrow transplantation (BMT) or hematopoietic stem cell transplantation (HSCT) is an archetype of cellular therapy. However, to date BMT still suffers from several complications. Recent technological advances have encouraged us to think about an alternative to traditional BMT. Specifically, we propose in utero HSCT (IUHSCT). For this purpose, we suggest that induced fetal-like hematopoietic stem cells (ifHSCs) might be suitable for IUHSCT, and should be seriously evaluated. ...[more]
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