Ontology highlight
ABSTRACT:
SUBMITTER: Kojima M
PROVIDER: S-EPMC7471656 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Kojima Machiko M Sone Kenbun K Oda Katsutoshi K Hamamoto Ryuji R Kaneko Syuzo S Oki Shinya S Kukita Asako A Kawata Akira A Honjoh Harunori H Kawata Yoshiko Y Kashiyama Tomoko T Sato Masakazu M Taguchi Ayumi A Miyamoto Yuichiro Y Tanikawa Michihiro M Tsuruga Tetsushi T Nagasaka Kazunori K Wada-Hiraike Osamu O Osuga Yutaka Y Fujii Tomoyuki T
Oncology letters 20200824 5
Previous studies have suggested that histone methylation can modulate carcinogenesis and cancer progression. For instance, the histone methyltransferase SET and MYND domain containing 2 (SMYD2) is overexpressed in several types of cancer tissue. The aim of the present study was to determine whether SMYD2 could serve a therapeutic role in ovarian clear cell carcinoma (OCCC). Reverse transcription-quantitative PCR was used to examine SMYD2 expression in 23 clinical OCCC specimens. Moreover, OCCC c ...[more]