Ontology highlight
ABSTRACT:
SUBMITTER: Nastase A
PROVIDER: S-EPMC7472447 | biostudies-literature | 2020 Sep-Oct
REPOSITORIES: biostudies-literature
Cancer genomics & proteomics 20200901 5
<h4>Background/aim</h4>Patients with stage IIIA (N2) non-small cell lung cancer (NSCLC) with no progression after induction chemotherapy are usually selected for surgery. Nowadays, response to chemotherapy is not predictable. We aimed to identify genomic predictive markers for response to induction chemotherapy in stage IIIA (N2) NSCLC patients.<h4>Patients and methods</h4>Whole-exome sequencing (WES) was performed on samples from 11 patients with no response after induction chemotherapy and 6 p ...[more]