Ontology highlight
ABSTRACT:
SUBMITTER: Gu M
PROVIDER: S-EPMC7472694 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Frontiers in physiology 20200821
Non-syndromic tooth agenesis (NSTA) is one of the most common dental abnormalities. MiRNAs participated in the craniofacial and tooth development. Therefore, single nucleotide polymorphisms (SNPs) in miRNA genes may contribute to the susceptibility of non-syndromic tooth agenesis. Here, a total of 625 non-syndromic tooth agenesis cases and 1,144 healthy controls were recruited, and four miRNA SNPs (<i>miR-146a</i>/rs2910164, <i>miR-196a2</i>/rs11614913, <i>pre-miR-605</i>/rs2043556, <i>pre-miR-6 ...[more]