Ontology highlight
ABSTRACT:
SUBMITTER: Parra M
PROVIDER: S-EPMC7473529 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Parra Marcela M Weitner Megan M Yang Amy A Akue Adovi A Liu Xia X Schmidt Thomas T Allman Windy R WR Akkoyunlu Mustafa M Derrick Steven C SC
PloS one 20200904 9
To better understand anti-malaria protective immune responses, we examined the cellular mechanisms that govern protective immunity in a murine Plasmodium yoelii 17X NL (PyNL) re-infection model. Initially, we confirmed that immune B cells generated during a primary PyNL infection were largely responsible for protection from a second PyNL infection. Using the previously identified memory B cell markers CD80, PD-L2, and CD73, we found an increase in the frequency of CD80-PD-L2-CD73+ B cells up to ...[more]