Ontology highlight
ABSTRACT:
SUBMITTER: Jonsson H
PROVIDER: S-EPMC7474095 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Jonsson Hans H Hugerth Luisa W LW Sundh John J Lundin Eva E Andersson Anders F AF
Communications biology 20200904 1
Segmented filamentous bacteria (SFB) are unique immune modulatory bacteria colonizing the small intestine of a variety of animals in a host-specific manner. SFB exhibit filamentous growth and attach to the host's intestinal epithelium, offering a physical route of interaction. SFB affect functions of the host immune system, among them IgA production and T-cell maturation. Until now, no human-specific SFB genome has been reported. Here, we report the metagenomic reconstruction of an SFB genome fr ...[more]