Ontology highlight
ABSTRACT:
SUBMITTER: Zhang SX
PROVIDER: S-EPMC7476641 | biostudies-literature | 2018 Jul
REPOSITORIES: biostudies-literature
Zhang Stephen X SX Miner Lauren E LE Boutros Christine L CL Rogulja Dragana D Crickmore Michael A MA
Neuron 20180705 2
We reveal a central role for chance neuronal events in the decision of a male fly to court, which can be modeled as a coin flip with odds set by motivational state. The decision is prompted by a tap of a female with the male's pheromone-receptor-containing foreleg. Each tap evokes competing excitation and inhibition onto P1 courtship command neurons. A motivating dopamine signal desensitizes P1 to the inhibition, increasing the fraction of taps that successfully initiate courtship. Once courtshi ...[more]