The frequency gradient of human resting-state brain oscillations follows cortical hierarchies.

ABSTRACT: The human cortex is characterized by local morphological features such as cortical thickness, myelin content, and gene expression that change along the posterior-anterior axis. We investigated if some of these structural gradients are associated with a similar gradient in a prominent feature of brain activity - namely the frequency of oscillations. In resting-state MEG recordings from healthy participants (N = 187) using mixed effect models, we found that the dominant peak frequency in a brain area decreases significantly along the posterior-anterior axis following the global hierarchy from early sensory to higher order areas. This spatial gradient of peak frequency was significantly anticorrelated with that of cortical thickness, representing a proxy of the cortical hierarchical level. Th

SUBMITTER: Mahjoory K 

PROVIDER: S-EPMC7476753 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature