Prehabilitation in patients awaiting elective coronary artery bypass graft surgery - effects on functional capacity and quality of life: a randomized controlled trial.

ABSTRACT: OBJECTIVE:To determine the impact of an exercise-based prehabilitation (EBPrehab) program on pre- and postoperative exercise capacity, functional capacity (FC) and quality of life (QoL) in patients awaiting elective coronary artery bypass graft surgery (CABG). DESIGN:A two-group randomized controlled trail. SETTING:Ambulatory prehabilitation. SUBJECTS:Overall 230 preoperative elective CABG-surgery patients were randomly assigned to an intervention (IG, n?=?88; n?=?27 withdrew after randomization) or control group (CG, n?=?115). INTERVENTION:IG: two-week EBPrehab including supervised aerobic exercise. CG: usual care. MAIN MEASURES:At baseline (T1), one day before surgery (T2), at the beginning (T3) and at the end of cardiac rehabilitation (T4) the following measurements were performed: cardiopulmonary exercise test, six-minute walk test (6MWT), Timed-Up-and-Go Test (TUG) and QoL (MacNew questionnaire). RESULTS:A total of 171 patients (IG, n?=?81; CG, n?=?90) completed the study. During EBPrehab no complications occurred. Preoperatively FC (6MWTIG: 443.0?±?80.1?m to 493.5?±?75.5?m, P?=?0.003; TUGIG: 6.9?±?2.0?s to 6.1?±?1.8?s, P?=?0.018) and QoL (IG: 5.1?±?0.9 to 5.4?±?0.9, P?

SUBMITTER: Steinmetz C 

PROVIDER: S-EPMC7477776 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature