Ontology highlight
ABSTRACT:
SUBMITTER: Iyer VS
PROVIDER: S-EPMC7479249 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Computational and structural biotechnology journal 20200818
Over the last decade Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) has been developed into a potent molecular biology tool used to rapidly modify genes or their expression in a multitude of ways. In parallel, CRISPR-based screening approaches have been developed as powerful discovery platforms for dissecting the genetic basis of cellular behavior, as well as for drug target discovery. CRISPR screens can be designed in numerous ways. Here, we give a brief background to CRISPR ...[more]