Unknown

Dataset Information

0

Selective Binding of Dopamine and Epinephrine in Water by Molecularly Imprinted Fluorescent Receptors.


ABSTRACT: Catecholamines play important roles in biology but their structural similarity makes it challenging to construct synthetic receptors with selective binding. A combination of covalent and noncovalent binding groups in the hydrophobic core of water-soluble nanoparticles enabled them to recognize dopamine and epinephrine with an association constant (Ka ) of 3-4×104  M-1 in water, an order of magnitude higher than those of previously reported synthetic hosts. In addition, minute structural changes among analogues were detected including the addition or removal of a single hydroxyl or methyl group.

SUBMITTER: Duan L 

PROVIDER: S-EPMC7480134 | biostudies-literature |

REPOSITORIES: biostudies-literature

Similar Datasets

| S-EPMC5010460 | biostudies-literature
| S-EPMC7472588 | biostudies-literature
| S-EPMC7303128 | biostudies-literature
| S-EPMC8232576 | biostudies-literature
| S-EPMC7277882 | biostudies-literature
| S-EPMC5906172 | biostudies-literature
| S-EPMC11359759 | biostudies-literature
| S-EPMC6566530 | biostudies-literature
| S-EPMC8694954 | biostudies-literature
| S-EPMC7022724 | biostudies-literature