Ontology highlight
ABSTRACT:
SUBMITTER: Dicker K
PROVIDER: S-EPMC7482619 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Dicker Kate K Järvelin Aino I AI Garcia-Moreno Manuel M Castello Alfredo A
Seminars in cell & developmental biology 20200910
RNA is a central molecule in RNA virus biology due to its dual function as messenger and genome. However, the small number of proteins encoded by viral genomes is insufficient to enable virus infection. Hence, viruses hijack cellular RNA-binding proteins (RBPs) to aid replication and spread. In this review we discuss the 'knowns' and 'unknowns' regarding the contribution of host RBPs to the formation of viral particles and the initial steps of infection in the newly infected cell. Through compar ...[more]