Ontology highlight
ABSTRACT:
SUBMITTER: Cheng R
PROVIDER: S-EPMC7482638 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Cheng Rong R Li Wei W Sample Klarke M KM Xu Qiang Q Liu Lin L Yu Fuxun F Nie Yingjie Y Zhang Xiangyan X Luo Zhenhua Z
PeerJ 20200907
Candida parapsilosis is a major fungal pathogen that leads to sepsis. New and more effective antifungal agents are required due to the emergence of resistant fungal strains. MAF-1A is a cationic antifungal peptide isolated from Musca domestica that is effective against a variety of Candida species. However, the mechanism(s) of its antifungal activity remains undefined. Here, we used RNA-seq to identify differentially expressed genes (DEGs) in Candida parapsilosis following MAF-1A exposure. The e ...[more]