Ontology highlight
ABSTRACT:
SUBMITTER: Bubier JA
PROVIDER: S-EPMC7486296 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Bubier Jason A JA He Hao H Philip Vivek M VM Roy Tyler T Hernandez Christian Monroy CM Bernat Rebecca R Donohue Kevin D KD O'Hara Bruce F BF Chesler Elissa J EJ
Scientific reports 20200911 1
In the U.S., opioid prescription for treatment of pain nearly quadrupled from 1999 to 2014. The diversion and misuse of prescription opioids along with increased use of drugs like heroin and fentanyl, has led to an epidemic in addiction and overdose deaths. The most common cause of opioid overdose and death is opioid-induced respiratory depression (OIRD), a life-threatening depression in respiratory rate thought to be caused by stimulation of opioid receptors in the inspiratory-generating region ...[more]