Ontology highlight
ABSTRACT:
SUBMITTER: Lv P
PROVIDER: S-EPMC7486299 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Lv Peng P Ma Dongyuan D Gao Shuai S Zhang Yifan Y Bae Young-Ki YK Liang Guixian G Gao Suwei S Choi Jung-Hwa JH Kim Cheol-Hee CH Wang Lu L Liu Feng F
Stem cell reports 20200820 3
Cell transplantation into immunodeficient recipients is a widely used approach to study stem cell and cancer biology; however, studying cell states post transplantation in vivo is inconvenient in mammals. Here, we generated a foxn1/Casper mutant zebrafish that is transparent and exhibits T cell deficiency. By employing the line for hematopoietic stem cell (HSC) transplantation (HSCT), we could achieve nonconditioned transplantation. Meanwhile, we found that fetal HSCs from 3 days post fertilizat ...[more]