Ontology highlight
ABSTRACT:
SUBMITTER: Ordonez CD
PROVIDER: S-EPMC7490695 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Ordóñez Carlos D CD Lechuga Ana A Salas Margarita M Redrejo-Rodríguez Modesto M
Scientific reports 20200914 1
The development of whole genome amplification (WGA) and related methods, coupled with the dramatic growth of sequencing capacities, has changed the paradigm of genomic and genetic analyses. This has led to a continual requirement of improved DNA amplification protocols and the elaboration of new tailored methods. As key elements in WGA, identification and engineering of novel, faithful and processive DNA polymerases is a driving force in the field. We have engineered the B-family DNA polymerase ...[more]