Ontology highlight
ABSTRACT:
SUBMITTER: Qian J
PROVIDER: S-EPMC7679446 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Qian Jason J Boswell Sarah A SA Chidley Christopher C Lu Zhi-Xiang ZX Pettit Mary E ME Gaudio Benjamin L BL Fajnzylber Jesse M JM Ingram Ryan T RT Ward Rebecca H RH Li Jonathan Z JZ Springer Michael M
Nature communications 20201120 1
Rapid, inexpensive, robust diagnostics are essential to control the spread of infectious diseases. Current state of the art diagnostics are highly sensitive and specific, but slow, and require expensive equipment. Here we report the development of a molecular diagnostic test for SARS-CoV-2 based on an enhanced recombinase polymerase amplification (eRPA) reaction. eRPA has a detection limit on patient samples down to 5 viral copies, requires minimal instrumentation, and is highly scalable and ine ...[more]