Ontology highlight
ABSTRACT:
SUBMITTER: Minaga K
PROVIDER: S-EPMC7495433 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Minaga Kosuke K Watanabe Tomohiro T Hara Akane A Kamata Ken K Omoto Shunsuke S Nakai Atsushi A Otsuka Yasuo Y Sekai Ikue I Yoshikawa Tomoe T Yamao Kentaro K Takenaka Mamoru M Chiba Yasutaka Y Kudo Masatoshi M
Scientific reports 20200916 1
IgG4-related disease (IgG4-RD) is a multi-organ autoimmune disease characterized by elevated serum IgG4 concentration. Although serum IgG4 concentration is widely used as a biomarker for IgG4-RD and type 1 autoimmune pancreatitis (AIP), a pancreatic manifestation of IgG4-RD, a significant number of patients have normal serum IgG4 levels, even in the active phase of the disease. Recently, we reported that the development of experimental AIP and human type 1 AIP is associated with increased expres ...[more]