Ontology highlight
ABSTRACT:
SUBMITTER: Vyas VK
PROVIDER: S-EPMC7496949 | biostudies-literature | 2020 May
REPOSITORIES: biostudies-literature
Angewandte Chemie (International ed. in English) 20200701 34
The sulfone functional group has a strong capacity to direct the asymmetric transfer hydrogenation (ATH) of ketones in the presence of [(arene)Ru(TsDPEN)H] complexes by adopting a position distal to the η<sup>6</sup> -arene ring. This preference provides a means for the prediction of the sense of asymmetric reduction. The sulfone group also facilitates the formation of a range of reduction substrates, and its ready removal provides a route to enantiomerically enriched alcohols that would otherwi ...[more]