Ontology highlight
ABSTRACT:
SUBMITTER: Dufour JF
PROVIDER: S-EPMC7497577 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Dufour Jean-François JF Caussy Cyrielle C Loomba Rohit R
Gut 20200507 10
Non-alcoholic steatohepatitis (NASH) is becoming a leading cause of cirrhosis with the burden of NASH-related complications projected to increase massively over the coming years. Several molecules with different mechanisms of action are currently in development to treat NASH, although reported efficacy to date has been limited. Given the complexity of the pathophysiology of NASH, it will take the engagement of several targets and pathways to improve the results of pharmacological intervention, w ...[more]